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Monday, October 12, 2020 | History

3 edition of Mechanisms in respiratory toxicology found in the catalog.

Mechanisms in respiratory toxicology

Mechanisms in respiratory toxicology

  • 93 Want to read
  • 11 Currently reading

Published by CRC Press in Boca Raton, Fla .
Written in English

    Subjects:
  • Lungs -- Diseases,
  • Respiratory organs -- Diseases,
  • Pulmonary toxicology,
  • Lungs -- Pathology,
  • Lung diseases -- Chemically induced

  • Edition Notes

    Includes bibliographies and indexes.

    Statementeditors, Hanspeter Witschi, Paul Nettesheim.
    ContributionsWitschi, Hanspeter., Nettesheim, Paul.
    Classifications
    LC ClassificationsRC732 .M43 1982
    The Physical Object
    Pagination2 v. :
    ID Numbers
    Open LibraryOL4256702M
    ISBN 10084935689X, 0849356903
    LC Control Number81002135

    Purchase Clinical Veterinary Toxicology - 1st Edition. Print Book & E-Book. ISBN , Handbook of Toxicology. Edited by T. J. Haley and W. O. Berndt. Hemisphere Publishing Corporation, London, pp. xiv + £ ISBN Very few toxicologists, when asked to name the 'bible' of their chosen occupation, would fail to respond with the tome by Casarett and Doull.

    The book also includes new chapters on topics of timely interest such as radiation, food safety, and natural toxins. As in previous editions, chapters combine background material in the appropriate discipline—which helps readers review and remember the basics—with new information on toxicology to stress key principles and concepts. toxicology testing for pharmaceuticals for agrochemicals mechanism) Phase I: Late stage cancer patients, tolerance, kinetics, Respiratory + follow up/ supplemental studies as needed. Genetic toxicology and Carcinogenicity (ICH S2 (R2) & S1) Reproductive toxicologyFile Size: 1MB.

    Regulatory Toxicology, Third Edition This practical book provides toxicologists with essential information on the regulations that govern their jobs and products. Regulatory Toxicology, Third Edition is an up-to-date guide to required safety assessment for the entire range of man-made marketed products. In book: Clinical Toxicology: Principles and Mechansims, Edition: 2nd, Publisher: Informa HealthCare Publishers, Editors: Frank A. Barile Cite this publication Frank A Barile.


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Mechanisms in respiratory toxicology Download PDF EPUB FB2

Mechanisms in Respiratory Toxicology: 1st Edition. by M.D. Witschi, Hanspeter (Author), M.D. Nettesheim, Paul (Author) ISBN ISBN X.

Why is ISBN important. ISBN. This bar-code number lets you verify that you're getting exactly the right version or edition of a book Author: M.D. Witschi, Hanspeter.

Mechanisms In Respiratory Toxicology, Vol Ii: Medicine & Health Science Books @ ISBN: X OCLC Number: Description: 2 volumes: illustrations ; 27 cm: Contents: v.

--Delivery of Toxic Agents to the Lung --Comparative Morphology and Structure of the Airways / Joan Gil --Deposition and Clearance of Inhaled Aerosols / Otto G.

Raabe --Structure of the Blood and Lymph Vascular System in the Lung / Lee V. INTRODUCTION. Toxic substances can disrupt the respiratory system and distant organs after chemicals enter the body by means of inhalation. Pathological changes in the respiratory tract also can be a target of blood-borne agents.

Inhalation toxicology refers to the route of exposure, whereas respiratory toxicology refers to target organ toxicity.

A brief introduction to the structure and function of the respiratory system is followed by a summary of the reasons for susceptibility of this organ system to chemically‐induced injury.

Types of toxic response such as irritation, cell necrosis, fibrosis, emphysema, allergic responses and cancer are discussed as are mediators of toxic responses. For that reason, pulmonary toxicology cannot be understood without a firm grasp of host defense mechanisms.

Concepts of the respiratory tract as a target organ have changed fundamentally in the. The evidence for underlying mechanisms of respiratory injury from exposure to secondhand smoke suggests that a safe level of exposure may not exist, thus implying that any exposure carries some risk.

The respiratory system is relevant in toxicology as a target of toxic effects, and also as a major route of absorption of inhaled gases and atmospheric particles. If inhalation and subsequent absorption reach a toxic threshold, inhaled chemicals have the potential to produce lung disease.

The comparative physiology of respiratory mechanisms. This book explains the following topics: The Call For Oxygen, The Access To Oxygen, The Forces Acting In The Transport Of Oxygen (and C02) Through Living Tissues, Respiration In Water, Emergency Respiration-the Transition To Air Breathing, Respiration In Air, The Respiratory Functions Of Blood And Tracheal Respiration.

Clinical Toxicology: Diagnosis and treatment of poisoning; evaluation of methods of detection and intoxication, mechanism of action in humans (human tox, pharmaceutical tox) and animals (veterinary tox).

Integrates toxicology, clinical medicine, clinical Respiratory Dermal (skin)File Size: 1MB. Mechanistic toxicology is the study of how chemical or physical agents interact with living organisms to cause toxicity.

Knowledge of the mechanism of toxicity of a substance enhances the ability to prevent toxicity and design more desirable chemicals; it constitutes the basis for therapy upon overexposure, and frequently enables a further understanding of fundamental biological processes.

The most complex path to toxicity involves more steps (Figure 3–1).First, the toxicant is delivered to its target or targets (step 1), interacting with endogenous target molecules (step 2a) or altering the environment (step 2b), triggering perturbations in cell function and/or structure (step 3), which initiate repair mechanisms at the molecular, cellular, and/or tissue levels (step 4).

In “General Toxicology” the vastness of the toxicological scope is presented by outlining the possible encounter with toxicants of different origins, their fate in the human body and the effects produced.

The book smoothly introduces the reader to the basic principles and mechanisms in the body exposed to ubiquitous foreign substances. The Toxicology Handbook is written for hospital-based doctors at all levels and is divided into six sections, including an approach to the poisoned patient, specific toxins, antidotes, toxinology and antivenom.

It also deals with specific toxicology considerations like alcohol abuse, dependence and withdrawal, and poisoning in children and the. COX inhibitors and renal system pathophysiology and mechanisms of toxicity The pathophysiologic role of COX inhibition in the ocular system COX inhibition and the respiratory and cardiovascular systems.

The book also sheds light on the latest research devoted to. The comparative physiology of respiratory mechanisms. This book explains the following topics: The Call For Oxygen, The Access To Oxygen, The Forces Acting In The Transport Of Oxygen (and C02) Through Living Tissues, Respiration In Water, Emergency Respiration-the Transition To Air Breathing, Respiration In Air, The Respiratory Functions Of.

Section 4 Molecular and Biochemical Aspects of Organ Toxicology 19 Molecular Mechanisms of Respiratory Toxicity James C.

Bonner. Introduction Anatomy and Function of the Respiratory Tract Toxicant ]Induced Lung Injury, Remodeling, and Repair Occupational and Environmental Lung Diseases Suggested.

Reading This chapter will focus on lung-specific toxicity including a discussion of basic lung anatomy and physiology, the basis for pulmonary toxicity including the principles of gas and particle deposition, dosimetry and metabolism and key pulmonary toxicants and their known or hypothesized mechanisms of action, and toxicological approaches to characterizing the effects of agents with known and unknown potential for respiratory effects.

This book. Book Description. Reflecting the broad and interdisciplinary nature of toxicology, this third edition of Principles of Toxicology explores the biochemical, physiological, and environmental aspects of the subject.

This new edition is updated and revised to include reference to several major new directions in the science of toxicology, including significant changes in thinking about cancer and. AIR POLLUTION MECHANISMS AND TOXICOLOGY. Home > ATS Conferences > ATS American Journal of Respiratory and Critical Care MedicineVolume Conference Abstracts Effects of Diesel Exposure in Proximal and Distal Respiratory Tract.

K Yoshizaki, JM Brito, VS Piccin. Toxicology is an international, peer-reviewed journal that publishes only the highest quality original scientific research and critical reviews describing hypothesis-based investigations into mechanisms of toxicity associated with exposures to xenobiotic chemicals, particularly as it relates to human health.

In this respect "mechanisms" is defined on both the macro (e.g. physiological.Veterinary Toxicology, 2nd edition is a unique single reference that teaches the basic principles of veterinary toxicology and builds upon these principles to offer an essential clinical resource for those practicing in the field.

This reference book is thoroughly updated with new chapters and the latest coverage of topics that are essential to research veterinary toxicologists, students, professors. All journal articles featured in Toxicology Mechanisms and Methods vol 30 issue 4.

Log in | Register Cart. Impact Factor. Toxicology Mechanisms and Methods. Impact Factor. Search in: Advanced search. Submit an article. New content alerts RSS. Subscribe.